Engineering the oleaginous yeast Yarrowia lipolytica for production of α-farnesene
نویسندگان
چکیده
منابع مشابه
Metabolic engineering of oleaginous yeast Yarrowia lipolytica for limonene overproduction
BACKGROUND Limonene, a monocyclic monoterpene, is known for its using as an important precursor of many flavoring, pharmaceutical, and biodiesel products. Currently, d-limonene has been produced via fractionation from essential oils or as a byproduct of orange juice production, however, considering the increasing need for limonene and a certain amount of pesticides may exist in the limonene obt...
متن کاملRecent advances in bioengineering of the oleaginous yeast Yarrowia lipolytica
The oleaginous yeast, Yarrowia lipolytica, is becoming increasing popular for metabolic engineering applications. Advances in synthetic biology and metabolic engineering have allowed microorganisms such as Y. lipolytica to be tailored for specific chemical production. Significant progress has been made to understand the genetics of Y. lipolytica and towards developing novel genetic engineering ...
متن کاملLipid production by the oleaginous yeast Yarrowia lipolytica using industrial by-products under different culture conditions
BACKGROUND Microbial lipid production using renewable feedstock shows great promise for the biodiesel industry. RESULTS In this study, the ability of a lipid-engineered Yarrowia lipolytica strain JMY4086 to produce lipids using molasses and crude glycerol under different oxygenation conditions and at different inoculum densities was evaluated in fed-batch cultures. The greatest lipid content,...
متن کاملDevelopment of a cultivation process for the enhancement of human interferon alpha 2b production in the oleaginous yeast, Yarrowia lipolytica
BACKGROUND As an oleaginous yeast, Yarrowia lipolytica is able to assimilate hydrophobic substrates. This led to the isolation of several promoters of key enzymes of this catabolic pathway. Less is known about the behavior of Y. lipolytica in large bioreactors using these substrates. There is therefore a lack of established know-how concerning high cell density culture protocols of this yeast. ...
متن کاملEngineering of Yarrowia lipolytica for production of astaxanthin
Astaxanthin is a red-colored carotenoid, used as food and feed additive. Astaxanthin is mainly produced by chemical synthesis, however, the process is expensive and synthetic astaxanthin is not approved for human consumption. In this study, we engineered the oleaginous yeast Yarrowia lipolytica for de novo production of astaxanthin by fermentation. First, we screened 12 different Y. lipolytica ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biotechnology for Biofuels
سال: 2019
ISSN: 1754-6834
DOI: 10.1186/s13068-019-1636-z